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Anatomy of protein disorder, flexibility and disease-related mutations

Integration of protein structural information with human genetic variation and pathogenic mutations is essential to understand molecular mechanisms associated with the effects of polymorphisms on protein interactions and cellular processes. We investigate occurrences of non-synonymous SNPs in ordere...

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Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Lu, Hui-Chun, Chung, Sun Sook, Fornili, Arianna, Fraternali, Franca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532925/
https://ncbi.nlm.nih.gov/pubmed/26322316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00047
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