Wordt geladen...

Combined loss of the BH3-only proteins Bim and Bmf restores B-cell development and function in TACI-Ig transgenic mice

Terminal differentiation of B cells depends on two interconnected survival pathways, elicited by the B-cell receptor (BCR) and the BAFF receptor (BAFF-R), respectively. Loss of either signaling pathway arrests B-cell development. Although BCR-dependent survival depends mainly on the activation of th...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cell Death Differ
Hoofdauteurs: Woess, C, Tuzlak, S, Labi, V, Drach, M, Bertele, D, Schneider, P, Villunger, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532784/
https://ncbi.nlm.nih.gov/pubmed/25698446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.8
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!