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Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress associated IL-1

While recent studies suggest that IL-1β production is modulated by macroautophagy or sensors of ER stress upon pro-inflammatory insult, autophagy and IL-1β production during viral infection has not been fully investigated. This was addressed using respiratory syncytial virus (RSV), which is associat...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Reed, Michelle, Morris, Susan H., Owczarczyk, Anna B., Lukacs, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532659/
https://ncbi.nlm.nih.gov/pubmed/25669150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.3
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