IL-27R–Mediated Regulation of IL-17 Controls the Development of Respiratory Syncytial Virus–Associated Pathogenesis

IL-27 is a heterodimeric cytokine composed of the subunits p28 and Epstein-Barr virus induced gene (EBI)-3 and is known for its effects on T-cell function and differentiation. IL-27 signals through the widely expressed IL-27 receptor (IL-27R), composed of the ligand-specific IL-27Rα chain and gp130....

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Detalhes bibliográficos
Main Authors: de Almeida Nagata, Denise E., Demoor, Tine, Ptaschinski, Catherine, Ting, Hung-An, Jang, Sihyug, Reed, Michelle, Mukherjee, Sumanta, Lukacs, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044717/
https://ncbi.nlm.nih.gov/pubmed/24726498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.02.004
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