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Sirtuin 1 regulates dendritic cell activation and autophagy during Respiratory Syncytial Virus-induced immune responses

Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in children worldwide. Sirtuin 1 (SIRT1), an NAD(+) dependent deacetylase, has been associated with the induction of autophagy and the regulation of inflammatory mediators. We found that Sirt1 was upregulated i...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Owczarczyk, Anna B., Schaller, Matthew A., Reed, Michelle, Rasky, Andrew J., Lombard, David B., Lukacs, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530059/
https://ncbi.nlm.nih.gov/pubmed/26157176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500326
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