Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells

Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in children worldwide. Sirtuin 1 (SIRT1), a NAD+ dependent deacetylase, has been associated with induction of autophagy, reprogramming cellular metabolism, and regulating immune mediators. In this study, we inv...

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Publicado en:PLoS Pathog
Autores principales: Elesela, Srikanth, Morris, Susan B., Narayanan, Samanthi, Kumar, Surinder, Lombard, David B., Lukacs, Nicholas W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046194/
https://ncbi.nlm.nih.gov/pubmed/32106265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008319
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