Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation

Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif...

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Bibliographic Details
Published in:PLoS One
Main Authors: Hwang, Jun-Ha, Byun, Mi Ran, Kim, A. Rum, Kim, Kyung Min, Cho, Hang Jun, Lee, Yo Han, Kim, Juwon, Jeong, Mi Gyeong, Hwang, Eun Sook, Hong, Jeong-Ho
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532446/
https://ncbi.nlm.nih.gov/pubmed/26262877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135519
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