Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation

Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif...

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Vydáno v:PLoS One
Hlavní autoři: Hwang, Jun-Ha, Byun, Mi Ran, Kim, A. Rum, Kim, Kyung Min, Cho, Hang Jun, Lee, Yo Han, Kim, Juwon, Jeong, Mi Gyeong, Hwang, Eun Sook, Hong, Jeong-Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532446/
https://ncbi.nlm.nih.gov/pubmed/26262877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135519
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