Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation

Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hwang, Jun-Ha, Byun, Mi Ran, Kim, A. Rum, Kim, Kyung Min, Cho, Hang Jun, Lee, Yo Han, Kim, Juwon, Jeong, Mi Gyeong, Hwang, Eun Sook, Hong, Jeong-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532446/
https://ncbi.nlm.nih.gov/pubmed/26262877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135519
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