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Chronic Insulin Exposure Induces ER Stress and Lipid Body Accumulation in Mast Cells at the Expense of Their Secretory Degranulation Response

Lipid bodies (LB) are reservoirs of precursors to inflammatory lipid mediators in immunocytes, including mast cells. LB numbers are dynamic, increasing dramatically under conditions of immunological challenge. We have previously shown in vitro that insulin-influenced lipogenic pathways induce LB bio...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Greineisen, William E., Maaetoft-Udsen, Kristina, Speck, Mark, Balajadia, Januaria, Shimoda, Lori M. N., Sung, Carl, Turner, Helen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532411/
https://ncbi.nlm.nih.gov/pubmed/26263026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130198
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