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Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma

Despite recent advances in targeted therapies and immunotherapies metastatic melanoma remains only rarely curable. The objective of the present study was to identify novel therapeutic targets for metastatic melanoma. A library of 160 well-characterised and potent protein kinase inhibitors was screen...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Oncol
Prif Awduron: MAHGOUB, T., EUSTACE, A.J., COLLINS, D.M., WALSH, N., O'DONOVAN, N., CROWN, J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532220/
https://ncbi.nlm.nih.gov/pubmed/26201960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3097
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