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Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma

Despite recent advances in targeted therapies and immunotherapies metastatic melanoma remains only rarely curable. The objective of the present study was to identify novel therapeutic targets for metastatic melanoma. A library of 160 well-characterised and potent protein kinase inhibitors was screen...

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Detalles Bibliográficos
Publicado en:Int J Oncol
Main Authors: MAHGOUB, T., EUSTACE, A.J., COLLINS, D.M., WALSH, N., O'DONOVAN, N., CROWN, J.
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532220/
https://ncbi.nlm.nih.gov/pubmed/26201960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3097
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