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Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma

Despite recent advances in targeted therapies and immunotherapies metastatic melanoma remains only rarely curable. The objective of the present study was to identify novel therapeutic targets for metastatic melanoma. A library of 160 well-characterised and potent protein kinase inhibitors was screen...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: MAHGOUB, T., EUSTACE, A.J., COLLINS, D.M., WALSH, N., O'DONOVAN, N., CROWN, J.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532220/
https://ncbi.nlm.nih.gov/pubmed/26201960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3097
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