Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.
The SCL gene encodes a member of the helix-loop-helix family of transcription factors that have been implicated in regulation of differentiation and development. Although SCL mRNA is not detectable in normal thymocytes or peripheral T-lymphocytes, transcriptional activation occurs in T-cell tumours....
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| 發表在: | EMBO J |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
1991
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1756722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04993.x |
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