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Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.
The SCL gene encodes a member of the helix-loop-helix family of transcription factors that have been implicated in regulation of differentiation and development. Although SCL mRNA is not detectable in normal thymocytes or peripheral T-lymphocytes, transcriptional activation occurs in T-cell tumours....
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1991
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC453166/ https://ncbi.nlm.nih.gov/pubmed/1756722 |
| タグ: |
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