Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.

The SCL gene encodes a member of the helix-loop-helix family of transcription factors that have been implicated in regulation of differentiation and development. Although SCL mRNA is not detectable in normal thymocytes or peripheral T-lymphocytes, transcriptional activation occurs in T-cell tumours....

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Publié dans:	EMBO J
Auteurs principaux:	Green, A R, DeLuca, E, Begley, C G
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1756722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04993.x
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