The antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunction

Tert-butylhydroquinone (TBHQ) is an antioxidant compound which shows multiple cytoprotective actions. We evaluated the effects of TBHQ on pathological cardiac remodeling and dysfunction induced by chronic overload. Pressure overload was created by transverse aortic constriction (TAC) in male C57BL/6...

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Publicado en:Sci Rep
Main Authors: Zhang, Yongtao, Fang Liu, Fang, Bi, Xiaolei, Wang, Shuangxi, Wu, Xiao, Jiang, Fan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531315/
https://ncbi.nlm.nih.gov/pubmed/26260024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13005
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