The antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunction

Tert-butylhydroquinone (TBHQ) is an antioxidant compound which shows multiple cytoprotective actions. We evaluated the effects of TBHQ on pathological cardiac remodeling and dysfunction induced by chronic overload. Pressure overload was created by transverse aortic constriction (TAC) in male C57BL/6...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zhang, Yongtao, Fang Liu, Fang, Bi, Xiaolei, Wang, Shuangxi, Wu, Xiao, Jiang, Fan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531315/
https://ncbi.nlm.nih.gov/pubmed/26260024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13005
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