The antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunction

Tert-butylhydroquinone (TBHQ) is an antioxidant compound which shows multiple cytoprotective actions. We evaluated the effects of TBHQ on pathological cardiac remodeling and dysfunction induced by chronic overload. Pressure overload was created by transverse aortic constriction (TAC) in male C57BL/6...

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發表在:Sci Rep
Main Authors: Zhang, Yongtao, Fang Liu, Fang, Bi, Xiaolei, Wang, Shuangxi, Wu, Xiao, Jiang, Fan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531315/
https://ncbi.nlm.nih.gov/pubmed/26260024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13005
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