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The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

The nuclear form of the NF-kappa B transcription factor binds to DNA as a heterodimer of a 50 kDa (p50) and 65 kDa (p65) polypeptide. The two polypeptides are encoded by different genes but share a long region of homology, the NRD motif, encompassing domains required for DNA binding and dimerization...

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Bibliografiske detaljer
Main Authors: Schmitz, M L, Baeuerle, P A
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC453117/
https://ncbi.nlm.nih.gov/pubmed/1935902
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