The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.
The nuclear form of the NF-kappa B transcription factor binds to DNA as a heterodimer of a 50 kDa (p50) and 65 kDa (p65) polypeptide. The two polypeptides are encoded by different genes but share a long region of homology, the NRD motif, encompassing domains required for DNA binding and dimerization...
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| Udgivet i: | EMBO J |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1935902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04950.x |
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