The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

The nuclear form of the NF-kappa B transcription factor binds to DNA as a heterodimer of a 50 kDa (p50) and 65 kDa (p65) polypeptide. The two polypeptides are encoded by different genes but share a long region of homology, the NRD motif, encompassing domains required for DNA binding and dimerization...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Schmitz, M L, Baeuerle, P A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1935902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04950.x
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