Surgical Downstaging in an Open-Label Phase II Trial of Denosumab in Patients with Giant Cell Tumor of Bone

BACKGROUND: Surgical resection with curative intent for giant cell tumor of bone (GCTB) may be associated with severe morbidity. This interim analysis evaluated reduction in surgical invasiveness after denosumab treatment in patients with resectable GCTB. METHODS: Patients with primary or recurrent...

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Detalhes bibliográficos
Publicado no:Ann Surg Oncol
Main Authors: Rutkowski, Piotr, Ferrari, Stefano, Grimer, Robert J., Stalley, Paul D., Dijkstra, Sander P. D., Pienkowski, Andrzej, Vaz, Gualter, Wunder, Jay S., Seeger, Leanne L., Feng, Amy, Roberts, Zachary J., Bach, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Bone and Soft Tissue Sarcomas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531146/
https://ncbi.nlm.nih.gov/pubmed/26033180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-015-4634-9
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