Denosumab treatment of inoperable or locally advanced giant cell tumor of bone

Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive tumor that rarely metastasizes and typically occurs in the bones. At present, the primary treatment for GCTB is curettage with local adjuvants. Giant cells express receptor activator of nuclear factor-κB ligand (RANKL). Denosumab,...

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Publicado no:Oncol Lett
Main Authors: Borkowska, Aneta, Goryń, Tomasz, Pieńkowski, Andrzej, Wągrodzki, Michał, Jagiełło-Wieczorek, Ewelina, Rogala, Paweł, Szacht, Milena, Rutkowski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228072/
https://ncbi.nlm.nih.gov/pubmed/28101196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5246
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