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Challenges of denosumab in giant cell tumor of bone, and other giant cell-rich tumors of bone
PURPOSE OF REVIEW: Giant cell tumor of bone (GCTB) is an uncommon benign primary bone tumor, consisting of receptor activator of nuclear factor kappa-B (RANK) expressing reactive osteoclast-like giant cells and neoplastic spindle-shaped cells. Denosumab was approved by FDA in 2013 and by EMA in 2014...
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| Yayımlandı: | Curr Opin Oncol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Lippincott Williams & Wilkins
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613724/ https://ncbi.nlm.nih.gov/pubmed/30844887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000529 |
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