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Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells

Metabolism is closely linked with cellular state and biological processes, but the mechanisms controlling metabolic properties in different contexts remain unclear. Cellular senescence is an irreversible growth arrest induced by various stresses, which exhibits active secretory and metabolic phenoty...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Takebayashi, Shin-ichiro, Tanaka, Hiroshi, Hino, Shinjiro, Nakatsu, Yuko, Igata, Tomoka, Sakamoto, Akihisa, Narita, Masashi, Nakao, Mitsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531082/
https://ncbi.nlm.nih.gov/pubmed/26009982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12351
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