Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells

Metabolism is closely linked with cellular state and biological processes, but the mechanisms controlling metabolic properties in different contexts remain unclear. Cellular senescence is an irreversible growth arrest induced by various stresses, which exhibits active secretory and metabolic phenoty...

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Publicat a:Aging Cell
Autors principals: Takebayashi, Shin-ichiro, Tanaka, Hiroshi, Hino, Shinjiro, Nakatsu, Yuko, Igata, Tomoka, Sakamoto, Akihisa, Narita, Masashi, Nakao, Mitsuyoshi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531082/
https://ncbi.nlm.nih.gov/pubmed/26009982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12351
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