LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα

Acute myeloid leukemia (AML) is a heterogenous malignancy characterized by distinct lineage subtypes and various genetic/epigenetic alterations. As with other neoplasms, AML cells have well-known aerobic glycolysis, but metabolic variations depending on cellular lineages also exist. Lysine-specific...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Kohrogi, Kensaku, Hino, Shinjiro, Sakamoto, Akihisa, Anan, Kotaro, Takase, Ryuta, Araki, Hirotaka, Hino, Yuko, Araki, Kazutaka, Sato, Tetsuya, Nakamura, Kimitoshi, Nakao, Mitsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114557/
https://ncbi.nlm.nih.gov/pubmed/33929501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003521
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