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STIL binding to Polo-box 3 of PLK4 regulates centriole duplication
Polo-like kinases (PLK) are eukaryotic regulators of cell cycle progression, mitosis and cytokinesis; PLK4 is a master regulator of centriole duplication. Here, we demonstrate that the SCL/TAL1 interrupting locus (STIL) protein interacts via its coiled-coil region (STIL-CC) with PLK4 in vivo. STIL-C...
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| Publicado en: | eLife |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530586/ https://ncbi.nlm.nih.gov/pubmed/26188084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07888 |
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