Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations

Highly redundant pathways often contain components whose functions are difficult to decipher from the responses induced by genetic or molecular perturbations. Here, we present a statistical approach that samples and registers events observed in images of intrinsic fluctuations in unperturbed cells t...

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Bibliographic Details
Published in:Cell Syst
Main Authors: Lee, Kwonmoo, Elliott, Hunter L., Oak, Youbean, Zee, Chih-Te, Groisman, Alex, Tytell, Jessica D., Danuser, Gaudenz
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530526/
https://ncbi.nlm.nih.gov/pubmed/26273703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2015.07.001
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