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Using Fluctuation Analysis to Establish Causal Relations between Cellular Events without Experimental Perturbation
Experimental perturbations are commonly used to establish causal relationships between the molecular components of a pathway and their cellular functions; however, this approach suffers inherent limitations. Especially in pathways with a significant level of nonlinearity and redundancy among compone...
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Publicado no: | Biophys J |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255263/ https://ncbi.nlm.nih.gov/pubmed/25468328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.032 |
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