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Using Fluctuation Analysis to Establish Causal Relations between Cellular Events without Experimental Perturbation

Experimental perturbations are commonly used to establish causal relationships between the molecular components of a pathway and their cellular functions; however, this approach suffers inherent limitations. Especially in pathways with a significant level of nonlinearity and redundancy among compone...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Welf, Erik S., Danuser, Gaudenz
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255263/
https://ncbi.nlm.nih.gov/pubmed/25468328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.032
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