Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration

We find how collective migration emerges from mechanical information transfer between cells. Local alignment of cell velocity and mechanical stress orientation—a phenomenon dubbed “plithotaxis”—plays a crucial role in inducing coordinated migration. Leader cells at the monolayer edge better align ve...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Zaritsky, Assaf, Welf, Erik S., Tseng, Yun-Yu, Angeles Rabadán, M., Serra-Picamal, Xavier, Trepat, Xavier, Danuser, Gaudenz
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699880/
https://ncbi.nlm.nih.gov/pubmed/26682808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.001
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