Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide.

Ítems similars

• The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
  per: Miyoshi, H, et al.
  Publicat: (1993)
• The AML1-MTG8 Leukemic Fusion Protein Forms a Complex with a Novel Member of the MTG8(ETO/CDR) Family, MTGR1
  per: Kitabayashi, Issay, et al.
  Publicat: (1998)
• RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis
  per: Yan, Ming, et al.
  Publicat: (2009)
• Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells
  per: Trombly, Daniel J, et al.
  Publicat: (2015)
• AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation
  per: Miyamoto, Toshihiro, et al.
  Publicat: (2000)