Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C.

Recent evidence has accumulated showing that activation of PLC-catalysed hydrolysis of phosphatidylcholine (PC-PLC) is a critical step in mitogenic signal transduction both in fibroblasts and in oocytes from Xenopus laevis. The products of ras genes activate PC-PLC, bind guanine nucleotides, have in...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Dominguez, I, Marshall, M S, Gibbs, J B, García de Herreros, A, Cornet, M E, Graziani, G, Diaz-Meco, M T, Johansen, T, McCormick, F, Moscat, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1655413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04884.x
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