Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C.

Recent evidence has accumulated showing that activation of PLC-catalysed hydrolysis of phosphatidylcholine (PC-PLC) is a critical step in mitogenic signal transduction both in fibroblasts and in oocytes from Xenopus laevis. The products of ras genes activate PC-PLC, bind guanine nucleotides, have in...

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Main Authors: Dominguez, I, Marshall, M S, Gibbs, J B, García de Herreros, A, Cornet, M E, Graziani, G, Diaz-Meco, M T, Johansen, T, McCormick, F, Moscat, J
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC453045/
https://ncbi.nlm.nih.gov/pubmed/1655413
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