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Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation

Analysis of brain ultrastructure using electron microscopy typically relies on chemical fixation. However, this is known to cause significant tissue distortion including a reduction in the extracellular space. Cryo fixation is thought to give a truer representation of biological structures, and here...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Korogod, Natalya, Petersen, Carl CH, Knott, Graham W
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530226/
https://ncbi.nlm.nih.gov/pubmed/26259873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05793
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