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Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation

Analysis of brain ultrastructure using electron microscopy typically relies on chemical fixation. However, this is known to cause significant tissue distortion including a reduction in the extracellular space. Cryo fixation is thought to give a truer representation of biological structures, and here...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Korogod, Natalya, Petersen, Carl CH, Knott, Graham W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530226/
https://ncbi.nlm.nih.gov/pubmed/26259873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05793
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