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Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation

Analysis of brain ultrastructure using electron microscopy typically relies on chemical fixation. However, this is known to cause significant tissue distortion including a reduction in the extracellular space. Cryo fixation is thought to give a truer representation of biological structures, and here...

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Publicat a:eLife
Autors principals: Korogod, Natalya, Petersen, Carl CH, Knott, Graham W
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530226/
https://ncbi.nlm.nih.gov/pubmed/26259873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05793
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