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TIM-1 signaling is required for Maintenance and Induction of regulatory B cells

Apart from their role in humoral immunity, B cells can exhibit IL-10-dependent regulatory activity (Bregs). These regulatory subpopulations have been shown to inhibit inflammation and allograft rejection. However, our understanding of Bregs has been hampered by their rarity, lack of a specific marke...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Yeung, Melissa Y., Ding, Qing, Brooks, Craig R., Xiao, Sheng, Workman, Creg J., Vignali, Dario A.A., Ueno, Takuya, Padera, Robert F., Kuchroo, Vijay K., Najafian, Nader, Rothstein, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530122/
https://ncbi.nlm.nih.gov/pubmed/25645598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13087
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