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Cysteine oxidation impairs systemic glucocorticoid responsiveness in children with difficult-to-treat asthma
BACKGROUND: The mechanisms underlying glucocorticoid responsiveness are largely unknown. Although redox regulation of the glucocorticoid receptor (GR) has been reported, it has not been studied in asthma. OBJECTIVE: We characterized systemic cysteine oxidation and its association with inflammatory a...
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| 出版年: | J Allergy Clin Immunol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530082/ https://ncbi.nlm.nih.gov/pubmed/25748343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.01.023 |
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