Airway TGFβ(1) and oxidant stress in children with severe asthma: Association with airflow limitation

BACKGROUND: Transforming growth factor beta-1 (TGFβ(1)) is thought to play a role in airway remodeling in asthma. TGFβ(1) expression may be mediated by an excessive burden of reactive oxygen species and oxidant stress. OBJECTIVE: Given the profound airway oxidant stress we have previously observed i...

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Autores principales: Brown, Sheena D., Baxter, Katherine M., Stephenson, Susan T., Esper, Annette M., Brown, Lou Ann S., Fitzpatrick, Anne M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268912/
https://ncbi.nlm.nih.gov/pubmed/22206775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.11.037
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