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Glutathione Oxidation Is Associated With Airway Macrophage Functional Impairment in Children With Severe Asthma

Airway cellular dysfunction is a differentiating feature of severe asthma in children that may be related to an imbalance of the antioxidant, glutathione (GSH). We hypothesized that oxidation of GSH to glutathione disulfide (GSSG) in the epithelial lining fluid (ELF) of children with severe asthma w...

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Detalhes bibliográficos
Main Authors: Fitzpatrick, Anne M., Teague, W. Gerald, Burwell, Leandrea, Brown, Meredith S., Brown, Lou Ann S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066054/
https://ncbi.nlm.nih.gov/pubmed/20975618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3182026370
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