Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor

Background: After an initial response to EGFR targeted therapy, secondary resistance almost invariably ensues, thereby limiting the clinical benefit of the drug. Hence, it has been recognized that the successful implementation of targeted therapy in the treatment of HNSCC cancer is very much depende...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Boeckx, Carolien, Blockx, Lina, de Beeck, Ken Op, Limame, Ridha, Camp, Guy Van, Peeters, Marc, Vermorken, Jan B, Specenier, Pol, Wouters, An, Baay, Marc, Lardon, Filip
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529614/
https://ncbi.nlm.nih.gov/pubmed/26269754
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