Anti-Epidermal Growth Factor Receptor Therapy in Head and Neck Squamous Cell Carcinoma: Focus on Potential Molecular Mechanisms of Drug Resistance

Targeted therapy against the epidermal growth factor receptor (EGFR) is one of the most promising molecular therapeutics for head and neck squamous cell carcinoma (HNSCC). EGFR is overexpressed in a wide range of malignancies, including HNSCC, and initiates important signal transduction pathways in...

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Detalhes bibliográficos
Main Authors: Boeckx, Carolien, Baay, Marc, Wouters, An, Specenier, Pol, Vermorken, Jan B., Peeters, Marc, Lardon, Filip
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2013
Assuntos:
Head and Neck Cancers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720640/
https://ncbi.nlm.nih.gov/pubmed/23821327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0013
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