Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo.

Specific DNA sequences from several DNase I hypersensitive sites located upstream of the tyrosine aminotransferase (TAT) gene are bound by ubiquitous nuclear factors in vitro. Genomic footprinting has shown, however, that proteins are excluded from their potential binding sites in cells where the ge...

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Bibliographic Details
Published in:EMBO J
Main Authors: Weih, F, Nitsch, D, Reik, A, Schütz, G, Becker, P B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1991
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1714382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07796.x
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