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Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data

Cell signaling underlies transcription/epigenetic control of a vast majority of cell-fate decisions. A key goal in cell signaling studies is to identify the set of kinases that underlie key signaling events. In a typical phosphoproteomics study, phosphorylation sites (substrates) of active kinases a...

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Bibliografische gegevens
Gepubliceerd in:PLoS Comput Biol
Hoofdauteurs: Yang, Pengyi, Zheng, Xiaofeng, Jayaswal, Vivek, Hu, Guang, Yang, Jean Yee Hwa, Jothi, Raja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529189/
https://ncbi.nlm.nih.gov/pubmed/26252020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004403
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