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Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data
Cell signaling underlies transcription/epigenetic control of a vast majority of cell-fate decisions. A key goal in cell signaling studies is to identify the set of kinases that underlie key signaling events. In a typical phosphoproteomics study, phosphorylation sites (substrates) of active kinases a...
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Publicado no: | PLoS Comput Biol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529189/ https://ncbi.nlm.nih.gov/pubmed/26252020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004403 |
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