Microstructural White Matter Properties Mediate the Association between APOE and Perceptual Speed in Very Old Persons without Dementia

BACKGROUND: Reduced white matter integrity, as indicated by lower fractional anisotropy (FA) and higher mean diffusivity (MD), has been related to poorer perceptual speed (PS) performance. As the ε4 allele has been associated with lower white matter integrity in old age, this represents a potential...

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Опубликовано в: :PLoS One
Главные авторы: Laukka, Erika J., Lövdén, Martin, Kalpouzos, Grégoria, Papenberg, Goran, Keller, Lina, Graff, Caroline, Li, Tie-Qiang, Fratiglioni, Laura, Bäckman, Lars
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529164/
https://ncbi.nlm.nih.gov/pubmed/26252210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134766
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