Microstructural White Matter Properties Mediate the Association between APOE and Perceptual Speed in Very Old Persons without Dementia

BACKGROUND: Reduced white matter integrity, as indicated by lower fractional anisotropy (FA) and higher mean diffusivity (MD), has been related to poorer perceptual speed (PS) performance. As the ε4 allele has been associated with lower white matter integrity in old age, this represents a potential...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Laukka, Erika J., Lövdén, Martin, Kalpouzos, Grégoria, Papenberg, Goran, Keller, Lina, Graff, Caroline, Li, Tie-Qiang, Fratiglioni, Laura, Bäckman, Lars
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529164/
https://ncbi.nlm.nih.gov/pubmed/26252210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134766
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