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Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
Mismatch repair prevents the accumulation of erroneous insertions/deletions and non-Watson–Crick base pairs in the genome. Pathogenic mutations in the MLH1 gene are associated with a predisposition to Lynch and Turcot’s syndromes. Although genetic testing for these mutations is available, robust cla...
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| Veröffentlicht in: | Acta Crystallogr F Struct Biol Commun |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528928/ https://ncbi.nlm.nih.gov/pubmed/26249686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15010183 |
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