Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma.

Lignende værker

• Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships.
  af: Peles, E, et al.
  Udgivet: (1993)
• Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3.
  af: Wallasch, C, et al.
  Udgivet: (1995)
• A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway.
  af: Ben-Levy, R, et al.
  Udgivet: (1994)
• Rotational Coupling of the Transmembrane and Kinase Domains of the Neu Receptor Tyrosine Kinase
  af: Bell, Charlotte A., et al.
  Udgivet: (2000)
• Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptor.
  af: Margolis, B, et al.
  Udgivet: (1990)